
Prevention begins with Protection
Protection begins with Bovilis®
Bovilis vaccines help farmers protect cattle from production losses and disease, giving them greater control of their herd’s health now and in the future.
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Why vaccinate for BVD?
BVD is endemic in New Zealand, affecting both dairy and beef herds.
BVD has been estimated to cost the New Zealand cattle industry around $150 million a year.
LIC Data shows the prevalance of BVD in dairy herds is high1
- 63% of dairy herds had a milk antibody level of >0.75
- 13% of herds contained milking PI animals.
The situation in beef herds in New Zealand is similar.
- In a comparative study2 of 94 low and high fertility beef herds, 65% were actively infected with BVD
- A more recent study3 of 43 beef herds showed 58% had evidence of recent BVD infection.
Economic modelling shows it pays to control BVD.
Andrew Weir's economic model showed the various means of BVD control and how these reduced the impact of BVD compared to no control.
Weir A. PhD work submitted June 2016.
Average discounted cost per year for an average 400 cow farm
* Only vaccinating milking heifers ** Calf vaccination then subsequent annual boosters until whole herd vaccination is achieved
Economic modelling showed it is always more cost effective to do something than to do nothing4.
Vaccination is a cost effective part of most control strategies.
Why Bovilis BVD?
The only BVD vaccine with a 12 month fetal protection claim*
Bovilis BVD is the only BVD vaccine with a 12 month fetal protection claim*
*Bovilis BVD provides 6 months fetal protection following the initial vaccination series (sensitiser and booster), and 12 months fetal protection following a third dose.
The key to BVD control is protecting the fetus to prevent PI calves being formed.
Flexible primary dosing interval
Made from the strain which is the predominant subtype in NZ
Bovilis BVD is made with strain C86, a Type 1a BVD virus which is the predominant subtype in NZ5.
- Australian isolates are predominantly subtype 1c6
- The C86 strain and adjuvant in Bovilis BVD are highly immunogenic7,8
- Bovilis BVD provides protection against diverse Type 1&2 BVD viruses, as well as Border Disease viruses7,8
No drop in milk production
Vaccinating with Bovilis BVD doesn't cause a drop in milk production.
New Zealand dairy herds are vaccinated when milk production is near its peak, so its important that a vaccine has no effect on milk production.
A field study has demonstrated no observable difference between vaccinated and control animals following vaccination, and no effect on average milk yields.10
12 months duration of immunity for transient infection
Bovilis BVD provides 12 months duration of immunity for transient infection.11
While transiently infected animals are not the main source of BVD spread within a herd it is the most frequent infection type and the cost of lost production from a transiently infected animal is significant.
Safe for use in pregnant cattle
Bovilis BVD is formulated for safety in pregnant cows.
In breeding cattle it is good practice to administer the booster vaccination no less than, but close to 4 weeks before the planned start of mating to ensure fetal protection in early gestation. Bovilis BVD is safe for use in pregnant cows which provides confidence in situations when there is an extended mating period. If any cattle are pregnant at the time of vaccination there will be no adverse effects for the cow or her unborn calf.
References
* Following a third dose (annual vaccination) Bovilis BVD provides 12 months fetal protection.
1. Voges, H. and Hill, F. BVD Steering Committee Roadshow 2014
2. Heuer, C. et al. (2008). Effect of reproductive pathogens on pregnancy rates in beef herds. Proc. 38th Sem. Soc. Sheep and Beef Cattle Vets. NZVA; 141-147
3. Cuttance, W & Cuttance. (2014) E. Analysis of individual farm investigations into bovine viral diarrhoea in beef herds in the North Island of New Zealand. NZ Vet J. Nov; 62(6): 338-42
4. Weir A. PhD work submitted June 2016
5. Horner GW et al. (2000) Typing of New Zealand strains of pestivirus. Surveillance 27(3):16
6. Mahony et al. (2005) Genetic analysis of bovine viral diarrhoea viruses from Australia. Veterinary Microbiology 106 1-6
7. Patel, J.R. et al. (2005) Variation in immunogenicity of ruminant pestiviruses as determined by the neutralisation assay, The Veterinary Journal, Vol 169, 468-472.
8. Makoschey, B et al. (2001) An inactivated bovine viral diarrhoea virus (BVDV) type 1 vaccine affords clinical protection against BVD type 2.
9. Mawhinney, I., (2005) Vaccination with Bovilis BVD-MD improves fertility in dairy herds under field conditions. Tierärztliche Umschau 60(9):501-502
10. MSD Data on file
11. Munoz Bielsa, J. et al. Evaluation of the level of protection afforded by a BVD inactivated vaccine (C-86 strain), 12 months after vaccination. Journees Nationales des GTV, Nantes, 2005, 903
Why vaccinate for BRD?
Vaccination is an important risk management strategy to prevent BRD.
Bovine Respiratory Disease (BRD) is one of the most common and costly diseases of cattle globally. Due to the intensification of farming in New Zealand, BRD may now have a larger impact than what we have seen historically. Most cattle are susceptible to BRD at some point in their lifetime and it can impact performance.
Why Bovilis MH+IBR?
Proven performance
Since its launch in 2011, Bovilis MH+IBR has been used extensively in the Australian cattle industry where it has been shown to be extremely effective at reducing levels of respiratory disease morbidity and mortality.
In a large Australian feedlot trial1, cattle vaccinated with 2 doses of Bovilis MH+IBR had significantly lower morbidity and mortality rates due to BRD than control cattle vaccinated with other vaccines.
Flexible primary dosing interval
Bovilis MH+IBR has a flexible primary dosing interval of 2 weeks to 9 months between the initial sensitiser and booster shots.
This extended vaccination interval allows farmers the convenience of aligning their vaccination schedule with other planned management practices.
Immunity from 14 days following the 2nd dose
Bovilis MH+IBR vaccine provides active immunity 14 days after the 2nd dose.
For this reason vaccination should take place in advance of situations with high potential for BRD to occur. These situations may involve weaning, transport, mixing of cattle, weather extremes, dust, handling and change of diet.
Safe for use in pregnant cattle
Bovilis MH+IBR is formulated for safety in pregnant cattle.
This means farmers can confidently administer the vaccine to all stock types concurrently knowing there will be no adverse effects for the cow or her unborn calf.
References
1. Bovilis MH+IBR Field Trials: 2009:001. ISPAH Data on file. Rhinogard™ , APVMA: 49679, Registered to Zoetis Australia Pty Limited
2. The MSD Veterinary Manual (9th edition)(2008). www.msdvetmanual.com
3. MLA, Controlling BRD in feedlot cattle, FL06, 2001
4. Bovilis MH+IBR Field Trials: 20019:001. MSD Data on file
Increases antibodies in colostrum and milk
Calves are born without antibodies to fight infection. They rely completely on high-quality colostrum for protection against scours-causing pathogens.
It is critical that calves receive enough of the right antibodies in colostrum, and then in transition milk, to reduce their risk of scours.
Rotavec Corona significantly elevates neutralising antibodies in colostrum and milk for at least 28 days post-calving3
Boosts levels of both G6 and G10 antibodies
Research shows Rotavec Corona vaccination boosts levels of both G6 and G10 antibodies.4
Cross-protection
Cows vaccinated with a single serotype produce antibodies to all serotypes to which they have had prior exposure. This response has been demonstrated by numerous researchers5,6,7 and is also observed with other viruses that have marked antigenic variability such as influenza.
Reduces environmental contamination.
Faeces from calves fed colostrum from Rotavec Corona vaccinated cows contain less virus. This results in reduced environmental contamination and less likelihood of virus spread to uninfected calves.4
Health risks & diseases
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